Biological Constructs for Preparing Nanostructured Two- and Three-Dimensional Materials

Chad A. Mirkin

Chemistry Department, Northwestern University, 2145 Sheridan Rd., Evanston, IL 60208, USA

e-mail: camirkin@chem.nwu.edu
 

Methods for guiding the formation of two- and three-dimensional nanostructures from DNA-modified nanoparticle building blocks and substrates will be described. Emphasis will be on both metal and quantum dot semiconductor structures and their unusual collective optical properties. Several schemes that utilize these nanostructures for DNA-diagnostic applications will be discussed. Finally, a new type of ultrahigh resolution soft-lithography that is interfaceable with biomolecules and biofuntionalized building blocks will be presented. This soft lithography allows one to pattern structures with 10 nm spatial and linewidth resolution with near-perfect alignment. Implications in materials synthesis, electronics, and biodiagnostics will be discussed.